Oct 2021

NEW PUBLICATION: Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L.

2023-07-18T16:00:19+02:00October 31st, 2021|Publications|

Structural and Biochemical Analysis of the Dual Inhibition of MG-132 against SARS-CoV-2 Main Protease (Mpro/3CLpro) and Human Cathepsin-L.

Costanzi, E., Kuzikov, M., Esposito, F., Albani, S., Demitri, N., Giabbai, B., Camasta, M., Tramontano, E., Rossetti, G., Zaliani, A., Storici, P.

International journal of molecular sciences, 22(21), 11779:

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Mar 2021

NEW PUBLICATION: A blueprint for high affinity SARS-CoV-2 Mpro inhibitors from activity-based compound library screening guided by analysis of protein dynamics

2023-07-18T16:49:12+02:00March 16th, 2021|Publications|

A blueprint for high affinity SARS-CoV-2 Mpro inhibitors from activity-based compound library screening guided by analysis of protein dynamics

Gossen, J., Albani, S., Hanke, A., Joseph, B.P., Bergh, C., Kuzikov, M., Costanzi, E., Manelfi, C., Storici, P., Gribbon, P., Beccari, A.R., Talarico, C., Spyrakis, F., Lindahl, E., Zaliani, A., Carloni, P., Wade, R.C., Musiani, F., Kokh,

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Mar 2021

NEW PUBLICATION: Identification of inhibitors of SARS-CoV-2 3CL-pro enzymatic activity using a small molecule in vitro repurposing screen

2023-07-18T17:09:07+02:00March 13th, 2021|Publications|

Identification of inhibitors of SARS-CoV-2 3CL-pro enzymatic activity using a small molecule in vitro repurposing screen

ACS Pharmacology & Translational Science: https://doi.org/10.1021/acsptsci.0c00216

Kuzikov, M., Costanzi, E., Reinshagen, J., Esposito, F., Vangeel, L., Wolf, M., Ellinger, B., Claussen, C., Geisslinger, G., Corona, A., Iaconis, D., Talarico, C., Manelfi, C., Cannalire, R.,

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Mar 2021

NEW PUBLICATION: The Expression of the Cancer-Associated lncRNA Snhg15 Is Modulated by EphrinA5-Induced Signaling

2023-07-18T17:01:48+02:00March 12th, 2021|Publications|

The Expression of the Cancer-Associated lncRNA Snhg15 Is Modulated by EphrinA5-Induced Signaling

Daniel Pensold; Julia Gehrmann; Georg Pitschelatow; Asa Walberg; Kai Braunsteffer; Julia Reichard; Armin Ravaei; Jenice Linde; Angelika Lampert; Ivan G. Costa; Geraldine Zimmer-Bensch

International Journal of Molecular Science 2021, 22, 1332. https://doi.org/10.3390/ijms22031332

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